Brain Tumors: "Boost-Enhanced Intensity-Modulated Radiation Therapy (IMRT) in Brain Tumors"

In a "boost" IMRT treatment, the dense center of the tumor is given a higher dose of radiation. The greater the radiation dose we can administer there, the longer the tumor should be kept under control.

Side effects may be slightly increased with a higher tumor dose, but it is the side effects at the margins of the tumor that are especially relevant and, in this area, the radiation dose is not higher than in previous treatments.

This protocol has already been tested on several patients. None of the patients had much stronger or even intolerable side effects and we consider this new treatment to be safe for this reason.

With the following research project, we want to show that the 10% higher radiation dose in the tumor's center can significantly delay the tumor's regrowth or further growth and that the animals can be free of symptoms for a longer period and live longer (and better!).

 

Which patients can participate?
Dogs with brain tumors

What is required of you and your pet?

  • The patients are randomized for this experiment. This means that the lot will determine whether they are treated with the conventional or with the +10% boost radiation protocol.
  • To observe the improved tumor control in a standardized manner, a control CT or MRI is required at 6 and 12 months.
  • We will call you every 3 months to find out how your pet is doing.


What is the benefit of participating?

  • It supports cancer research.
  • The patient is irradiated with the normal or a potentially better treatment protocol.
  • A large part of the costs for control CT or MRI examinations at 6 and 12 months can be covered by a foundation.